Review: Effects of Moringa oleifera-Derived Prebiotics on Gut Health and Physiological Responses in Broiler Chickens

Abstract

This literature review aims to summarize scientific evidence on the effects of Moringa oleifera-derived prebiotics on gut health and physiological responses in broiler chickens. A systematic search was conducted using Scopus, PubMed, and Google Scholar databases, focusing on experimental and observational studies published over the last ten years. The reviewed literature indicates that Moringa oleifera, particularly its leaf polysaccharide fraction (Moringa oleifera leaf polysaccharides/MOLP), exerts its primary biological effects through prebiotic mechanisms rather than direct antimicrobial activity. Non-digestible polysaccharides and soluble fibers are selectively utilized by beneficial gut microbiota, leading to increased populations of Lactobacillus spp. and Bacteroides, suppression of pathogenic bacteria, enhanced short-chain fatty acid production, and improved intestinal morphology and gut barrier integrity. These microbiota-mediated effects contribute to improved immune regulation, antioxidant capacity, and hematological and metabolic profiles, ultimately resulting in better growth performance and feed efficiency. Overall, the available evidence supports the classification of Moringa oleifera as a prebiotic-like functional feed additive with strong potential for application in antibiotic-free and sustainable poultry production systems.