Antihyperglycemic and antioxidant activity of Bajakah herbal tea made from Bajakah rod-Tikung honey-Amblycarpa lime (jeruk Sambal) [Aktivitas antihiperglikemia dan antioksidan minuman teh herbal Bajakah yang dibuat dari madu Tikung-batang Bajakah-jeruk Sambal]

Authors

  • Aristawipana Marina Tanjungpura University
  • Oke Anandika Lestari Tanjungpura University
  • Yohana Sutiknyawati Kusuma Dewi Tanjungpura University

DOI:

https://doi.org/10.23960/jtihp.v30i1.23-34
Abstract View: 276

Keywords:

Bajakah rod, Tikung honey, Amblycarpa lime (jeruk Sambal), Anti-hyperglycemic, Antioxidant

Abstract

Hyperglycemia is characterized by elevated blood glucose levels, defined as instant blood glucose exceeding 200 mg/dL or fasting blood glucose surpassing 126 mg/dL. This condition has the potential to increase free radicals in the body. Using herbal ingredients or herbal drinks can also be a way to control blood glucose and free radicals. The Uncaria genus has functional anti-diabetic properties because it contains alkaloids and flavonoid compounds with antihyperglycemic and antioxidant effects. This study aimed to measure the antioxidant and antihyperglycemic potential of bajakah herbal tea with its raw materials (bajakah wood extract, honey, and Amblycarpa lime (jeruk Sambal)). The formulation of Bajakah herbal tea consists of 19.32 g Amblycarpa lime (jeruk Sambal), 46.38 g Bajakah rod extract, and 57.97 g honey. Antioxidant activity was achieved using the 2,2-diphenyl-1-picrylhydrazyl or DPPH method, and antihyperglycemic methods were used, such as the Oral Glucose Tolerance Test (OGTT). Physical characteristics are also tested for pH, color, and total dissolved solids. Data was analyzed using one-way ANOVA. The results showed that the combination of Bajakah-based herbal drinks, Bajakah herbal tea (123.67 g or equivalent to a carbohydrate content of 50 g), and the single preparation did not have antihyperglycemic activity. However, bajakah herbal tea has the highest antioxidant activity compared to its raw materials.

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References

AOAC. (2007). Official Method of Analysis of The Association of Official Analytical Chemists. Arlington: The Association of Official Analytical Chemists, Inc.

Al-Maqtari, Q. A., Rehman, A., Mahdi, A. A., Al-Ansi, W., Wei, M., Yanyu, Z., Phyo, H. M., Galeboe, O., & Yao, W. (2022). Application of essential oils as preservatives in food systems: challenges and future prospectives – a review. In Phytochemistry Reviews (Vol. 21, Issue 4). Springer Netherlands. https://doi.org/10.1007/s11101-021-09776-y

Anggraini, D., Radiati, L., & Purwadi, P. (2016). Carboxymethyl cellulose (CMC) addition In terms of taste, aroma, color, pH, viscosity, and turbidity of apple cider honey drink. Jurnal Ilmu Dan Teknologi Hasil Ternak, 11(1), 58–67. https://doi.org/10.21776/ub.jitek.2016.011.01.7

Anggriani, R., Harini, N., Husna, A., Sukardi, S., & NS, M. D. (2024). A new property of Bajakah Tampala Wood (Spatholobus littoralis Hassk) ethanol extract against α-Amylase Inhibition as candidate antidiabetic and Its fortification in Kapok Honey. Jurnal Teknologi dan Industri Pertanian Indonesia, 16(1), 62–69. https://doi.org/10.17969/jtipi.v16i1.28522

Azzahra, A., Farhani, N., Syahfitri, W., & Pasaribu, S. F. (2022). Potensi kandungan flavonoid dalam kayu Bajakah sebagai antidiabetes. Jurnal Pendidikan Tambusai, 6(2), 14345–14350. https://www.jptam.org/index.php/jptam/article/view/4708

Baldelli, A., Ren, M., Liang, D. Y., Lai, S., Hartono, B., Sum, K., & Pratap-Singh, A. (2023). Sprayed microcapsules of minerals for fortified food. Journal of Functional Foods, 101(December 2022), 105401. https://doi.org/10.1016/j.jff.2023.105401

Becerril‐sánchez, A. L., Quintero‐salazar, B., Dublán‐garcía, O., & Escalona‐buendía, H. B. (2021). Phenolic compounds in honey and their relationship with antioxidant activity, botanical origin, and color. Antioxidants, 10(11), 1–23. https://doi.org/10.3390/antiox10111700

Cheong, M. W., Zhu, D., Sng, J., Liu, S. Q., Zhou, W., Curran, P., and Yu, B. Characterisation of calamansi (Citrus microcarpa). Part II: Volatiles, physicochemical properties, and non-volatiles in the juice. (2012). Food Chemistry, 134, 696-703. http://dx.doi.org/10.1016/j.foodchem.2012.02.139

Dooley, T. P., Pérez, J. M. P., & Rodriquez, C. R. (2022). Stevia and Uncaria extract (GlucoMedix®) reduces glucose levels and the need for medications in type 2 diabetes: an open-label case series of six patients. Clinical Phytoscience, 8(1). https://doi.org/10.1186/s40816-021-00332-x

Fajarwati, I., Solihin, D. D., and Wresdiyati, T. (2024). Gambier for diabetes: comparison of the antidiabetic potency between two types of extracts from Uncaria gambir (W. Hunter) Roxb. Kefarmasian Indonesia Journal. 14(1), 51-62. DOI: https://doi.org/10.22435/jki.v14i1.6621

Ganogpichayagrai, A., & Suksaard, C. (2020). Proximate composition, vitamin and mineral composition, antioxidant capacity, and anticancer activity of Acanthopanax trifoliatus. Journal of Advanced Pharmaceutical Technology and Research, 11(4), 179–183. https://doi.org/10.4103/japtr.JAPTR_61_20

Hasna, L. Z., Sehkhaemi, P., & Aviciena, M. A. (2021). Review: akar kayu Bajakah dan manfaatnya untuk kesehatan. FoodTech: Jurnal Teknologi Pangan, 4(1), 32. https://doi.org/10.26418/jft.v4i1.56637

Ifada, A. S., Ningsih, A. I. F., & Dahlia, A. (2019). Studi preklinik : efek kombinasi madu dan serbuk biji Gorek (Caesalpinia Crista) terhadap kadar glukosa darah. Jikf, 7(2), 87–90. https://ejournal.unwmataram.ac.id/index.php/jikf/article/view/586

Karangan, J., Sugeng, B., & Sulardi, S. (2019). Uji keasaman air dengan alat sensor Ph Di Stt Migas Balikpapan. Jurnal Kacapuri : Jurnal Keilmuan Teknik Sipil, 2(1), 65. https://doi.org/10.31602/jk.v2i1.2065

Lestari, O. A., & Dewi, Y. S. K. (2023). Penerapan analisis multivariat untuk memetakan sifat fisikokimia dan mutu glikemik madu. Gorontalo Agriculture Technology Journal, 6(1), 25–36. https://doi.org/https://doi.org/10.32662/gatj.v0i0.2738

Lestari, O. A., Dewi, Y. S. K., & Putri, M. (2020). Mutu glikemik kue Bingke variasi umbi di kota Pontianak. Jurnal Mutu Pangan : Indonesian Journal of Food Quality, 7(2), 80–84. https://doi.org/10.29244/jmpi.2020.7.2.80

Lestari, O. A., Palupi, N. S., Setiyono, A., Kusnandar, F., & Dewi, N. Y. (2024). LC-MS metabolomics and molecular docking approaches to identify antihyperglycemic and antioxidant compounds from Melastoma malabathricum L. Leaf. Saudi Journal of Biological Sciences, 31(8), 104047. https://doi.org/10.1016/j.sjbs.2024.104047

Lestari, O. A., Palupi, N. S., Setiyono, A., Kusnandar, F., & Yuliana, N. D. (2022). In vitro antioxidant potential and phytochemical profiling of Melastoma malabathricum leaf water extract. Food Science and Technology, 42, 1–9. https://doi.org/10.1590/fst.92021

Masdar, H., Hakiki, M. R., Syahputra, M. R., Satriasumatri, T., Putri, D., Bunaya, R., & Juananda, D. (2021). Tes Toleransi Glukosa Oral (TTGO) Pasca Pemberian Suspensi Kedelai Dibanding Suspensi Tempe pada Tikus (Rattus norvegicus Galur Wistar) Diabetik. Health and Medical Journal, 3(2), 01–07. https://doi.org/10.33854/heme.v3i2.634

Mita, S. R., Husni, P., Putriana, N. A., Maharani, R., Hendrawan, R. P., Dewi, D. A. (2024). A Recent update on the potential use of catechins in cosmeceutical. Cosmetics. 11(1), 23. https://doi.org/10.3390/cosmetics11010023Munggari, I. P., Kurnia, D., Deawati, Y., & Julaeha, E. (2022). Current Research of Phytochemical, Medicinal and Non-Medicinal Uses of Uncaria Gambir Roxb.: A Review. Molecules, 27(19). https://doi.org/10.3390/molecules27196551

Narawati., Suryono, H., and Setiawan. (2020). Modification of chicken eggshell and lime extract (Citrus amblycarpa) for minimizing lead (Pb) level on blood cockles (Anadara granosa). Medico-legal. 20(1), 2305-2310. https://doi.org/10.37506/v20/iI/2020/mlu/194651

Nazir, N., Zahoor, M., Ullah, R., Ezzeldin, E., & Mostafa, G. A. E. (2021). Curative effect of catechin isolated from Elaeagnus Umbellata Thunb. Berries for diabetes and related complications in streptozotocin-induced Diabetic Rats Model. Molecules, 26(1). https://doi.org/10.3390/Molecules26010137

Paiva, de A., Gonçalves, D., Ferreira, P., Baldwin, E., & Cesar, T. (2019). Postprandial effect of fresh and processed orange juice on glucose metabolism, antioxidant activity, and prospective food intake. Journal of Functional Foods, 52(May 2018), 302–309. https://doi.org/10.1016/j.jff.2018.11.013

Pasanda, O. S., Indriati, S., Amri, Ma’ruf, A. A., & Al Hayah, M. T. S. (2022). Uji Aktivitas Antioksidan Dan Kadar Polifenol Daun Ketapang (Terminalia Catappa L.). Prosiding 6th Seminar Nasional Penelitian & PengabdianKepadaMasyarakat2022,64–74. https://jurnal.poliupg.ac.id/index.php/snp2m/article/view/3891

Putri, D. A., Nalurita, I., and Zulkarnaen. (2023). Optimization of antioxidant activity and characterization of probiotic cascara beverage fermented using water kafiar grain. Jurnal Teknologi 7 Industri Pertanian, 29(2): 109-121. https://doi.org/10.23960/jtihp.v29i2.109-121

Qin, N., Lu, X., Liu, Y., Qiao, Y., Qu, W., Feng, F., & Sun, H. (2021). Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry. European Journal of Medicinal Chemistry, 210, 112960. https://doi.org/10.1016/j.ejmech.2020.112960

Rasyiid, M., & Susandarini, R. (2020). Pollen diversity and secondary metabolites in honey produced by Apis dorsata binghami from Central Sulawesi, Indonesia. Journal of Pharmacognosy and Phytochemistry, 9(2),2305–2309. https://www.researchgate.net/publication/379568130_Pollen_diversity_and_secondary_metabolites_in_honey_produced_by_Apis_dorsata_binghami_from_Central_Sulawesi_Indonesia

Salas-Perez, L., Delgado, J. M. G., Preciado-Rangel, P., Fuentes, J. A. G., Garay, A. V., and Castruita, M. A. S. (2018). The application of citric acid increases the quality and antioxidant capacity of lentil sprouts. Revista mexicana de ciencias agrícolas. 9(10). https://doi.org/10.29312/remexca.v0i20.999

Setia, I. M. A., Tjiptaningrum, A., Angraini, D. I., & Ayu, P. R. (2021). Hubungan usia dengan nilai tes toleransi glukosa oral (TTGO) pada generasi pertama penderita diabetes melitus (DM) tipe 2. Jurnal Medula, 11(1), 100–106. https://www.journalofmedula.com/index.php/medula/article/view/199

Shaik, M. I., Hamdi, I. H., & Sarbon, N. M. (2023). A comprehensive review on traditional herbal drinks: Physicochemical, phytochemicals and pharmacology properties. Food Chemistry Advances, 3(September), 100460. https://doi.org/10.1016/j.focha.2023.100460

Simatupang, M. A. B., Dewi, Y. S. K., & Lestari, O. A. (2024). Karakteristik es krim susu kambing dengan penambahan sari jeruk sambal (Citrus amblycarpa). Jurnal Agritechno, 17(1), 1–10. https://doi.org/https://doi.org/10.70124/at.vi

Suhandy, D., Yulia, M., Kusumiyati., Suharyatun, S., and Waluyo, S. (2021). Investigation on the influence of dilution of honey samples for honey classification using UV spectroscopy and chemometrics. Jurnal Teknologi & Industri Hasil Pertanian, 26(2), 77-82. http://dx.doi.org/10.23960/jtihp.v26i2.72-82

Tran, N., Pham, B., & Le, L. (2020). Bioactive compounds in anti-diabetic plants: From herbal medicine to modern drug discovery. Biology, 9(9), 1–31. https://doi.org/10.3390/biology9090252

Treki, M. M. A., Ashikeen, M. N., & Baib, A. A. O. (2018). Effect of acid load (Citric acid) on Diabetes-Induced rats. International Journal of Medical Toxicology and Legal Medicine, 21(3), 212. https://doi.org/DOI: 10.5958/0974-4614.2018.00070.0

Uduwana, S., Abeynayake, N., and Wickramasinghe I. (20223). activity in infusions of green tea with bee honey and Citrus limonum extracts additives. Journal of Agriculture and Food Research. 12, 100571. https://doi.org/10.1016/j.jafr.2023.100571

Ullah, A., Munir, S., Badshah, S. L., Khan, N., Ghani, L., Poulson, B. G., Emwas, A., & Jaremko, M. (2020). Important flavonoids and their role as a therapeutic agent. Molecules, 25(5243), 1–39. https://doi.org/doi:10.3390/molecules25225243

Wardhani, H. A. K., Ratnasari, D., & Kotimah, S. N. (2022). Kualitas madu lebah Apis dorsata Desa Semalah Kabupaten Kapuas Hulu Kalimantan Barat. BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research), 9(2), 81. https://doi.org/10.33772/biowallacea.v9i2.28720

Yadikar, N., Ahmet, A., Zhu, J., Bao, X., Yang, X., Han, H., and Rozi, P. (2022). Exploring the mechanism of citric acid for treating glucose metabolism disorder induced by hyperlipidemia. Food Biochemistry. https://doi.org/doi: 10.1111/jfbc.14404

Yanti, S. N., & Chandra, V. E. (2021). Kajian metabolit sekunder dalam air perasan Jeruk Sambal (Citrus microcarpa Bunge) yang berasal dari Desa Kalimas, Kalimantan Barat. Journal of Pharmaceutical And Sciences, 4(2), 105–110. https://doi.org/10.36490/journal-jps.com.v4i2.66

Zandavar, H., & Afshari Babazad, M. (2023). Secondary metabolites: alkaloids and flavonoids in medicinal plants. Herbs and Spices - New Advances, March 1–28. https://doi.org/10.5772/intechopen.108030

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Published

2025-01-15

How to Cite

Marina, A., Lestari, O. A., & Dewi, Y. S. K. (2025). Antihyperglycemic and antioxidant activity of Bajakah herbal tea made from Bajakah rod-Tikung honey-Amblycarpa lime (jeruk Sambal) [Aktivitas antihiperglikemia dan antioksidan minuman teh herbal Bajakah yang dibuat dari madu Tikung-batang Bajakah-jeruk Sambal]. Jurnal Teknologi &Amp; Industri Hasil Pertanian, 30(1), 23–34. https://doi.org/10.23960/jtihp.v30i1.23-34